med's go on Instagram: "The desmopressin (DDAVP) test helps differentiate central DI from nephrogenic DI by assessing the kidney’s response to synthetic ADH (desmopressin). In central DI, where there is a deficiency of ADH, administration of desmopressin leads to a significant increase in urine osmolality (≥50% rise) because the kidneys are still responsive. In nephrogenic DI, where the kidneys are resistant to ADH, desmopressin has little or no effect on urine osmolality, as the defect lies in
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