Jul 1, 2017 · A. p16 immunohistochemistry is not recommended as a routine adjunct assessment when the biopsy interpretation is negative, CIN I or CIN III. Strong and diffuse block staining for p16 …

p16 (by immunohistochemistry) for anogenital carcinomas and premalignant lesions Negative (cytoplasmic only staining, patchy nonblock type staining or diffuse blush / weak intensity staining) …

Sep 17, 2025 · p16: diffuse and strong nuclear and cytoplasmic reactivity (block type staining); improper use / interpretation may lead to overdiagnosis of HSIL Surgical excision is the treatment of choice, …

Nov 20, 2019 · Cytomorphologic overlap Also p16 + and high risk HPV+ Adenoid cystic carcinoma, solid type Basaloid tumor cells with high N/C ratio and angulated nuclei CD117 (c-kit)+ p16 -, high risk …

Immunostains, routine stains and CD markers at PathologyOutlines.com

Sep 3, 2020 · Positive for both p16 (diffuse, block-like) and p53 (aberrant patterns, see Negative stains) Mimics: EEC with papillary architecture (villoglandular, small nonvillous papillae, micropapillae): Less …

Sep 17, 2025 · Cervix - LSIL / CIN I / low grade dysplasia - transient / self limited infection by human papillomavirus (low risk or high risk HPV)

Oct 18, 2022 · Diffuse p16 expression may suggest cervical origin of a squamous carcinoma Reactive / reparative Atypical polypoid adenomyoma: Polypoid lesion with prominent myofibroblastic stroma …

Oct 26, 2023 · Answer B is incorrect because Ki67 shows only a variable growth fraction as in many other lesions. Answer C is incorrect because p16 is overexpressed in HPV associated VIN. Answer …

Aug 28, 2025 · Serous carcinoma is a high grade endometrial carcinoma with complex papillary, solid or glandular architecture and marked cytologic atypia, similar to tubo-ovarian high grade serous …