T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...

Engineered BiTE molecule draws T cells to eliminate FAP+ modulated smooth muscle cells, reducing plaque burden across mouse atherosclerosis models.

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic ...

Researchers have developed two innovative tools to help us delve deeper into cell communication, offering spatial insight ...

Researchers identify altered expression of genes that worsens periodontitis among smokers, and a new target molecule ...

The human brain contains billions of connected neurons that collectively support different mental functions, including the ...

Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and ...

Abstract: Alzheimer's Disease (AD) presents a complex, heterogeneous pathology that is difficult to decode with traditional bulk or static transcriptomic approaches. Single-cell RNA sequencing ...

A study by scientists at BRIC-RGCB has shed light on brain development and the maintenance of neural stem cells. In a ...

Researchers used spatial transcriptomics to map gene expression in developing wheat spikes at single-cell resolution.

Type 2 diabetes (T2D) is a major chronic metabolic disease worldwide and is especially prevalent in older adults. Although many synthetic drugs are ...