Melissa Chabot's 8-year-old son, Owen, is creative, has a great memory and smiles a lot. His specialty is clocks, she said. He uses construction paper, tape, glue and markers to create cuckoo clocks, ...

Methotrexate significantly lowers systolic blood pressure in newly diagnosed RA patients compared to sulfasalazine, potentially reducing cardiovascular risk. The study provides prospective comparative ...

Intravenous immunoglobulin (IVIg) treatment improves disability, muscle strength and skin symptoms in people with dermatomyositis. These improvements may be large enough to be meaningful in daily life ...

Leflunomide and methotrexate are prescription drugs used to treat rheumatoid arthritis (RA). Methotrexate is also used to treat certain other conditions, including psoriasis. This article explains the ...

A research team, led by Professor Lin Xiang (first right) and Professor Shen Jiangang (second right), has discovered that combining the active ingredient of the Chinese medicine Astragalus ...

Disease-modifying drug therapies are being sought intensively for osteoarthritis (OA), but none have proved out thus far. A previous trial in patients with OA of the hand had found that methotrexate ...

Amoxicillin has interactions with some other drugs. Examples include warfarin, methotrexate, and allopurinol. Talk with your doctor to avoid potentially harmful effects from amoxicillin interactions.

For initial treatment of symptomatic pulmonary sarcoidosis, methotrexate appeared to work as well as prednisone over 24 weeks, the randomized PREDMETH trial showed. Mean change from baseline in the ...

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International ...

Randomized, Open-Label, Phase III Study of Tilsotolimod in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced Refractory Melanoma (ILLUMINATE-301) R1 compared induction ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...