Methods: Early and accurate diagnosis of central nervous system infections (CNSIs) is crucial for clinical treatment. Cerebrospinal fluid (CSF) analysis is considered the gold standard for diagnosis, ...

CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

Researchers have worked with global partners to identify and successfully implement an intervention package that has significantly improved the diagnosis and management of brain infections in ...

Investigators conducted a single-centre, retrospective cohort study of 783 adult patients in Austria who underwent diagnostic LP, most on an elective basis. The main outcome was any procedural ...

To treat my chronic inflammatory demyelinating polyneuropathy, I was given a 5-day induction dose of intravenous immunoglobulin. To treat my chronic inflammatory demyelinating polyneuropathy (CIDP), I ...

In our previous case-based review, I teased the opportunity to use biomarkers to increase the accuracy and expediency of the diagnosis of Alzheimer's disease (AD). These tests are no longer confined ...

Aneurysmal subarachnoid hemorrhage (aSAH) is a severe type of stroke that is associated with poor outcome. A subset of patients with aSAH will develop secondary complications, most notably delayed ...

A test that looks for genetic hallmarks of brain cancers in samples of cerebrospinal fluid can decrease the time to diagnosis and eliminate the need for invasive brain biopsies for some patients.