NMDA receptors, which are expressed at excitatory synapses throughout the central nervous system (CNS), mediate a wide range of brain processes, including the synaptic plasticity associated with ...

In recent years, the psychedelic compound psilocybin found in magic mushrooms has been widely tested for its antidepressant properties as it appears to have long-lasting effects on the brain after ...

Multi-electrode arrays (MEAs) provide a noninvasive interface with sub-millisecond temporal resolution and long-term, multi-site recordings, enabling ...

A research team led by McGill University has taken a close look at a long-standing idea about Parkinson’s disease and found ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

For centuries, humans have marveled at the strange theater of their nightly visions. We wake with fragments of impossible ...

The hippocampus is a forebrain structure located within the medial temporal lobe that consists of the subiculum, CA1, CA2, CA3 and dentate gyrus regions. The hippocampal formation also includes the ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...