Three new DNA markers have been developed to allow sizing and quantitation of linear and supercoiled, double-stranded DNA. The Kb DNA Ladder contains 15 linear fragments from 250 bp to 12 kb. Bands ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...

Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...