Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC). Moreover, apoptosis resistance of carcinoma cells provides an ...

Bcl-2 family proteins are highly conserved molecules that play a crucial role in regulating the release of apoptotic proteins from mitochondria. They possess Bcl-2 homology (BH) domains, which are ...

Patient-reported outcomes from the GARNET trial in patients with advanced or recurrent mismatch repair deficient (dMMR) colorectal cancer (CRC): A post hoc subgroup analysis.

Preliminary clinical evidence of Lisaftoclax overcoming venetoclax resistance in myeloid malignancies with a 31.8% overall ...

SUZHOU, China and ROCKVILLE, Md., Dec. 12, 2021 /PRNewswire/ -- Ascentage Pharma (6855.HK), a global biopharmaceutical company engaged in developing novel therapies for cancers, chronic hepatitis B ...

NORTH CHICAGO, Ill., April 12, 2016 /PRNewswire/ -- AbbVie ABBV, a global biopharmaceutical company, today announced the U.S. Food and Drug Administration (FDA) has granted accelerated approval of ...

Lisaftoclax monotherapy demonstrated significant and durable clinical efficacy and a manageable safety profile in patients ...