Early in the beginning of the COVID-19 pandemic, scientists predicted the coronavirus would mutate slowly. They were wrong. Hundreds of thousands of viral mutations and multiple seasonal waves later, ...

With every new infection, the pandemic coronavirus gets new chances to mutate and adapt, creating opportunities for the virus to evolve new variants that are better at dodging our immune systems and ...

Above: Cartoon model of the SARS-CoV-2 spike protein showing the different regions (or domains) that are associated with known viral mutations and antibodies can recognize and attach to. These include ...

EVEscape predicts future viral mutations, new variants using evolutionary, biological information. The COVID-19 pandemic seemed like a never-ending parade of SARS-CoV-2 variants, each equipped with ...

In a recent article published in the journal Cell, researchers used an integrative multiomics platform to understand severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern ...

Many viruses, particularly RNA viruses, mutate at a very high rate per genome per replication. One possible explanation is that high mutation rates are selected to meet the challenge of fluctuating ...

Researchers have developed EVE-Vax, a computational design tool that creates synthetic SARS-CoV-2 spike proteins mimicking future immune-evading variants. These designed proteins enable early ...

A new, faster, and more cost-effective molecular diagnostic tool, Intelli-OVI, has been developed. It offers the potential for continuous monitoring of emerging SARS-CoV-2 variants and provides an ...

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have created the most comprehensive map to date showing how antibodies attach to the SARS-CoV-2 virus, which causes ...

New AI tool called EVEscape uses evolutionary and biological information to predict how a virus could change to escape the immune system. The tool successfully predicted the most concerning new ...