Evo’s success wasn’t limited to proteins. When they tested a different toxin that had an RNA-based inhibitor, the system ...

The goal of my laboratory is to define the sequence-structure-function relationships that underpin mRNA regulation and non-coding function in cells. We aim to translate our findings into mechanistic ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 2 (January 11, 2011), pp. 498-503 (6 pages) Routine manipulation of cellular genomes is contingent upon ...

The structure of protein sets the foundation for its interaction with other molecules in the body and, therefore, determines its function. This article will cover the structural principles of proteins ...

Every function in a cell is associated with a particular protein or group of proteins, typically in a well-defined ...

Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...