Researchers identified LENG8 as a key RNA quality control protein that prevents defective RNA from leaving the nucleus. By ...

In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought. James E. Ferrell Jr is in the ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell’s nucleus. The ...

An international team of researchers has created the most detailed model yet of how cells regulate traffic through the nuclear pore complex—the gateway between a cell’s nucleus and its cytoplasm. The ...

Researchers have created an array of nanopillars that can breach the nucleus of a cell -- the compartment that houses our DNA -- without damaging the cell's outer membrane. This new 'gateway into the ...

How do cells ensure that the "blueprints" of genetic information-RNA are accurate and intact before they are exported from ...