New research finds that sleep is essential for protecting brain mitochondria by transferring toxic metabolic waste from neurons to glial cells for disposal.

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

When HHMI Investigator Amita Sehgal started studying sleep 25 years ago, the topic elicited a yawn from most biologists. "In the year 2000, if I had suggested to my department that we hire people ...

As axonal mitochondria are lost, changes in the subunits of eIF2 are seen which hamper translation and autophagy and cause the accumulation of proteins in cells. Tokyo, Japan – Researchers from Tokyo ...

Plant‐pathogenic fungi rely on finely tuned cellular processes to invade host tissues and sustain infection. This study ...

Autophagy is a process used by cells as a recycling system to transport and break down organelles and other cytosolic components, which become enveloped in a membrane called the autophagosome. When ...

Your brain is a metabolically fierce organ, punching way above its weight of two pounds to consume 20 to 25 percent of the body’s fuel supply. The brain’s energy-making machinery, centered in ...

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, ...