A mitochondrial enzyme, Ak4, strengthens immune defense by promoting mitochondrial DNA synthesis and enhancing macrophage ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

An enzyme that controls the maturation and long-term survival of immune cells called macrophages has been discovered, with implications for research on aging and inflammatory disease. Virtually all ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

Every year, sepsis kills roughly 11 million people worldwide, more than lung cancer and heart attacks combined. Despite ...

The white blood cells' typical role is to promote inflammation and stimulate the immune response, but researchers say some actually appear to temper inflammatory conditions and improve healing.

Right ventricular (RV) remodeling and dysfunction are serious cardiovascular consequences due to prolonged hypoxic exposure, ...

Researchers Sumika Kato, Takeo Kubo, and Taro Fukazawa of the University of Tokyo have discovered that c1qtnf3, a secreting factor, namely a protein molecule that is secreted by a cell and influences ...

Study finds that resident macrophages maintain eye pressure by clearing buildup in drainage tissues. Their loss increases ...