These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

Researchers report a new way to turn off the harmful immune attack that occurs during autoimmune diseases such as multiple sclerosis (MS), while keeping healthy functions of the immune system intact.

A recent paper in Nature Biomedical Engineering, by Dr. David J. Mooney demonstrated how a new vaccine can enhance and maintain lymph node function to boost immunity against cancer in mice. Mooney, a ...

These findings could guide the development and refinement of immune-based treatments for cancer and chronic infection," said Dr Tsui. "Furthermore, our research shows that rather than only focusing on ...

Vaccines trigger a notably rapid response in the stromal cells of draining lymph nodes within the first hours after administration. Researchers at the University of Turku and the InFLAMES Flagship in ...

Lymph nodes are a key part of the human immune system, whose primary function is to combat infections. The effectiveness of vaccines is based on their ability to trigger events in lymph nodes that ...

Dramatic changes in lymphatic vessel contraction and in the lymph nodes that drain inflamed joints are associated with disease progression and response to therapy in murine models of rheumatoid ...

A lymph node biopsy is a test that checks for disease in your lymph nodes. Lymph nodes are small, oval-shaped organs located in different parts of your body. They’re found close to internal organs ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...

The image is from a draining lymph node (approximately 2 mm in size) after vaccination. The green cells are stromal cells that line the lymph node sinuses. The lymphatic vessels of the lymph node are ...