Study findings support initial use of voclosporin-based triple immunosuppression including low-dose glucocorticoids for proteinuria reduction. Among trial patients with lupus nephritis, ...

Three-fourths of kidney transplant patients in a small trial avoided long-term immunosuppression using a donor-derived cellular therapy. No deaths, graft loss, or complications occurred in the ...

Patients receiving significant amount of immunosuppression prior to kidney transplantation should be counseled on these malignancy risks, according to investigators. Using immunosuppression to treat ...

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Early emicizumab ...

Islet transplantation has emerged over the past few decades as a potential cure for type 1 diabetes. However, transplantation efforts have faced setbacks as the immune system continues to eventually ...

PHOENIX — Immunosuppression is an independent risk factor for poorer outcomes in patients with cutaneous squamous cell carcinoma (cSCC), according to new research that was presented at the American ...

Of the numerous risks associated with immunotherapy for the prevention of rejection, cost is perhaps the most universal. In the USA and some other countries, the costs of immunosuppression make ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive ...