SALT LAKE CITY— For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified ...

This is an ASCO Meeting Abstract from the 2022 ASCO Genitourinary Cancers Symposium. This abstract does not include a full text component.

This study is led by Prof. Junbo Ge (Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases), Prof. Hua Li (Department of Cardiology, Zhongshan ...

Scientists spent decades uncovering the mechanisms that regulate the human body’s response to oxygen. The implications on the way we understand disease could be significant. This article was produced ...

The efficacy and adverse event profiles of HIF-PHIs may differ among agents. Although all hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) target the HIF pathway, the individual ...