Genetically modified animals are designed to contain the spread of pathogens. One prerequisite for the release of such organisms into the environment is that the new gene variant does not spread ...

Heterozygotes for the autosomal recessive disease cystlnosis are currently detected by measuring the cystine content of mixed leukocyte preparations. This method offers about 90% accuracy. The ...

When the cystic fibrosis (CF) gene was cloned in 1989, two radical new approaches to the management of the disease became possible. The most important was the prospect of somatic gene therapy. In this ...