A woman's skin has turned a bizarre blue-brown color after using skin-lightening cream. This condition, known as exogenous ochronosis, had been affecting the 55-year-old patient for a year before she ...

Ochronosis is a rare disorder which manifests as a bluish-black discoloration of the skin and mucosa. It is categorized into endogenous or exogenous forms. This form is also referred to as ...

The FDA is seeking to ban over-the-counter sales of skin bleaching drug products. The FDA cites the possible risk of cancer and skin discoloration from hydroquinone typically found in these products.

Tyrosinase (Tyr) catalyzes hydroquinone (HQ) oxidation via two main pathways. The HBQ pathway directly oxidizes HQ to 2-hydroxy-1,4-benzoquinone (HBQ), which dimerizes and forms hydroquinone-eumelanin ...

Use of skin bleaching creams may increase the risk of developing diabetes and other diseases, according to a study in Canadian Family Physician. When walking into many pharmacies or beauty supply ...

Ocular signs are present in at least 2/3 of the patients affected by hereditary ochronosis. [16–20] In our review scleral hyperpigmentations were the most common finding (Figure 2, left). Slightly ...