Researchers have identified 15-PGDH enzyme inhibition as a neuroprotective strategy in Parkinson's disease, with repurposable ...

A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction testing—replacing dozens of traditional experiments with just one. The ...

Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than 10 million people worldwide. While current therapies address disease symptoms, they do not ...

Parkinson’s disease is the second most common brain disease that causes the gradual loss of nerve cells, affecting more than ...

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Diabetes mellitus, particularly type 2, is characterised by impaired insulin secretion and reduced cellular responsiveness, leading to chronic hyperglycaemia and associated complications. A central ...

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

Folate coenzymes are pivotal for one-carbon transfers in nucleotide and amino acid metabolism. Microorganisms synthesise folate de novo, making the pathway an attractive target for antimicrobial and ...

A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by ...

Inhibiting the immune enzyme 15-PGDH protected against neuroinflammation in Parkinson’s disease (PD) models. As 15-PGDH ...