Nature

Overdispersion of allele frequency differences between populations: implications for meta-analyses of genotypic disease associations

Complex genetic diseases are those with multiple environmental and genetic components contributing to the cumulative risk. Case–control association studies of genetic polymorphisms in complex genetic ...
Nature

The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males

The study population included 99 young, male volunteers who gave informed, written consent. Only male subjects were selected because augmentation index has been shown to differ between male and female ...
JSTOR Daily

CYP2A6 Polymorphism Reveals Differences in Japan and the Existence of a Specific Variant in Ovambo and Turk Populations

CYP2A6 is a polymorphic enzyme, and CYP2A6 genotype has been shown to be associated with smoking habits and lung cancer. We investigated CYP2A6 polymorphism in Japanese from four different geographic ...
JSTOR Daily

MTHFR C677T Polymorphism among Meiteis of Manipur (India)

Background: The enzyme MTHFR catalyses the irreversible conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, which serves as a methyl donor in the reaction converting homocysteine ...