Using a mAb, referred to as 08L, we have identified a protein, of M r ≈ 140,000, associated with desmosomes of epithelial cells. The 08L antibody stained the intracellular side of lateral cell margins ...
Researchers from Osaka University find that patient-derived cardiomyocytes carrying a mutation associated with arrhythmogenic cardiomyopathy exhibit the decreased contraction and impaired desmosome ...
Mature desmosomes are the main adhesive junctions in epithelia and cardiac muscle. Now new work shows that the desmosomal protein desmoplakin is also essential for the maturation of adherens junctions ...
Researchers have found that induced pluripotent stem cell--derived cardiomyocytes from a patient with arrhythmogenic cardiomyopathy recapitulate the reduced contractility and impaired desmosome ...
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