Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...
Surface model of SpCas9–reverse transcriptase–pegRNA–target DNA complex. The prime editor, composed of a SpCas9 and a reverse transcriptase, reverse transcribes template sequence in pegRNA, resulting ...
Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly ...
RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...
Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...
Researchers use cryo-EM and optical tweezers to investigate how an antiviral interacts with the herpes simplex virus.
Most people have witnessed -- or rather smelled -- when a protein enzyme called sulfite reductase works its magic. This enzyme catalyzes the chemical reduction of sulfite to hydrogen sulfide. Hydrogen ...
If you've ever accidentally sliced yourself on a broken glass or a piece of paper, you may have noticed that the bleeding can be hard to stop. Scientists have long wondered how the cascade of events ...
As summer kicks into full gear and people are spending more time outside, there's one thing on many people's minds - ticks. Tick season is starting earlier and lasting longer, and ticks are popping up ...
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