The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

One of the most fundamental questions in biology is how a single fertilized egg produces the diverse cell types making up the body – from neurons and skin to muscle and blood – that bear the same ...

There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like ...

Refined stem cell protocol has delivered high-purity, glucose-responsive insulin-producing cells that restore blood sugar ...

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

In 2011, The Scientist featured Bergmann’s early work on stomata development. She now uses new omics tools to explore the ...

Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to ...

This is a useful study that seeks to elucidate the molecular mechanisms underlying spinal motor circuit assembly. The authors demonstrate that loss of Onecut transcription factors in spinal motor ...