Multidimensional chromatography has emerged as a viable alternative to gel-based separation protocols in high-throughput bottom-up proteomics in recent years. Although originally dominated by the ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...

The practice of bottom-up proteomics relies to a large extent on the separation performance that can be achieved with state-of-the-art nano LC-MS/MS equipment. Depending on the sample complexity or ...