A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy. This ...

Autophagy has been shown to be a key player in preventing aging and diseases of aging, including cancer, cardiovascular disease, diabetes, and neurodegeneration. Notably, research has shown that ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control ...

Researchers headed by a team at NYU Langone Health have discovered that a feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy. The ...

In a recent study published in the journal Neuron, researchers at the University of Cambridge and Newcastle University, UK, examined the relationship between autophagy, aging, and neurodegeneration.