All gonadal samples were fixed in 10% formalin and embedded in paraffin. At least one section from each gonad was stained with hematoxylin and eosin and assessed by a pathologist who was experienced ...

This study was published in ResearchSquare.com as a preprint and has not yet been peer reviewed. Treatment of patients with CAIS with either estradiol or testosterone also led to a small but ...

Researchers in Spain have designed a guideline for physicians and patients on androgen insensitivity syndrome (AIS), a rare condition in which a person is genetically male but has some or all of the ...

Previously referred to as testicular feminization, this condition is known as complete androgen insensitivity syndrome. It is an X-linked disorder in which the patients are genotypically male ...

Androgen insensitivity syndrome (AIS) is an X-linked genetic disorder of male sexual differentiation caused by mutations in the androgen receptor (AR) gene. A reliable genotype–phenotype correlation ...

The androgen receptor is a key transcriptional factor for the proper sex development -- especially in males -- and the physiological balance of all the tissues that express this receptor. The androgen ...

Steroid hormones, to which belong sex hormones like estrogen or testosterone, are important signaling molecules and are responsible among other things for controlling female and male phenotypic sex ...

The Telangana High Court granted relief to a married woman suffering from Complete Androgen Insensitivity Syndrome (CAIS) ...