The anaphase promoting complex/cyclosome (APC/C) is a 1.5-MDa ubiquitin ligase complex that initiates sister-chromatid separation and exit from mitosis by targeting cyclin B and securin for ...

The APC/C (anaphase-promoting complex; also known as the cyclosome) is an E3 ubiquitin ligase that mediates the ubiquitylation of key substrates for their degradation by the proteasome at precise ...

As in anaphase in mitosis (and unlike anaphase I in meiosis), the fibers pull the chromatids apart and toward opposite ends of the cells.

Prognostic significance of circulating tumor cell (CTC) levels at various times during first- and second-line chemotherapy for metastatic breast cancer (MBC). This is an ASCO Meeting Abstract from the ...

According to the theory old cells split into new cells and the formation of new cells is known as cell division or cell production. This was firstly observed by Flemming in 1882 but an extensive in ...

Interphase The cell spends most of its life in this phase. The DNA in chromosomes copies itself ready for mitosis. Prophase The DNA in chromosomes and their copies condenses to become more visible.