The development of the vertebrate nervous system relies on dynamic interactions between neurons and their environment, orchestrated in large part by neural cell adhesion molecules (NCAMs). Among these ...
Adhesion molecules are pivotal mediators of cell–cell and cell–matrix interactions that underpin immune surveillance, vascular integrity and tissue homoeostasis. In the cardiovascular system, members ...
By employing the CRIPSR-Cas9 genome editing tool to fluorescently label endogenous class IA PI3K and imaging the cells using single-molecule quantitative imaging, the researchers discovered that both ...
Study shows for the first time that different forms of cellular adhesion structures can interconvert
Cells form adhesion structures to anchor themselves in their environment. The coordinated assembly and disassembly of these adhesions also enables cells to move from one place to another. There are ...
Time-lapse movie of the hub molecule afadin when momentarily released from the cytoskeleton. Quickly, it convenes in droplets, revealing the mechanism it employs to direct cellular attachment to the ...
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