EurekAlert!

Coexistence of APC and KRAS mutations in familial adenomatous polyposis and endometrial cancer: A mini-review with case-based perspective

Researchers have discovered an unusual case where two well-known cancer-related mutations—APC and KRAS—coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...
News Medical

Rare coexistence of APC and KRAS mutations observed in patient with FAP and endometrial cancer

Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...
ascopubs.org

Outcomes in patients with pancreatic and ampullary cancer whose tumors harbor pathogenic APC mutations.

New cutoff of CA19-9 values for predicting pancreatic cancer using liquid biopsy. This is an ASCO Meeting Abstract from the 2024 ASCO Gastrointestinal Cancers Symposium. This abstract does not include ...
ascopubs.org

Nirogacestat in patients with desmoid tumors and mutations of adenomatous polyposis coli (APC): Findings from the DeFi trial.

Total neoadjuvant therapy with FOLFOX plus bevacizumab and short-course radiotherapy for Ras mutant, high-risk, locally advanced rectal cancer: The TRAINER trial. Phase Ib study of gevokizumab (GEVO) ...
EurekAlert!

Advances and challenges in targeted therapy for colorectal cancer: A focus on adenomatous polyposis coli and kirsten rat sarcoma virus mutations

APC, adenomatous polyposis coli; CBP, cAMP-response element binding protein; CIBP, calcium- and integrin-binding protein; CK, creatine kinase. CtBP, C-terminal binding protein; GRO, growth-regulated ...