At the recent American Society of Hematology annual meeting, researchers presented preclinical data examining how ...

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets ...

Flagship Pioneering, a scientific innovation engine for transformative platforms and products, today announced a research program under its strategic collaboration with Pfizer whereby Flagship-founded ...

T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Creating physiologically relevant conditions for cells that replicate in vivo environments can improve experimental results, ...

Scripps Research scientists find that certain gut bacteria are essential for building immune defenses during infancy, pointing to new strategies for protecting children’s health.

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets ...